Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of PFN1 in human tissue homogenates, cell lysates.
Target Information: This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1. [provided by RefSeq, Jul 2012]